Schedule for Spring 2008

Mechanisms and Clinical Presentation of Pain 

(MSNBIO 2622, 3 semester hours)

Mondays and Thursdays, 3:30 - 5:00 p.m., 1495 BSTWR

G.F. Gebhart, Course Director
E-mail: gebhartgf@upmc.edu
Phone: 412-383-5911
Location: W1444 BSTWR

DateTopicPresenterReading Assignments
10 JanuaryCourse organization, pain terminology, pain overview
Pain Fellows case reports:
  • Juan Albino-Rodriguez
  • Robert Castro
  • Asif Chaudhry

G. Gebhart*

All

- Melzack & Wall (1965) - Pain mechanisms: A new theory
- E. Perl (2006) - Ideas about pain, a historical view
14 JanuaryPain Fellows case reports:
  • Brendan Coughtry
  • John Groner
  • Dean Mozeleski
All 
16 JanuaryLuda Diatchenko-UNC
Seminar
AllExpansion of the Genomic Architecture of the Human Mu Opioid Receptor Reveals a Novel Functional SNP
1105A Scaife Hall
17 JanuaryPain Fellows case reports:
  • Scott Palmer
  • Eric Robinson
  • Andrea Tan
All 
21 JanuaryNo Class - Martin Luther King Holiday
  
24 JanuaryNociceptors IB.Davis* 
28 JanuaryNociceptors II / Dorsal horn structure and function-IB.Davis* / K. Koeber*
 
31 January
Dorsal horn structure and function –II
R. Koeber* 
04 FebruaryAscending pathways (sensory and affective)D. Molliver* 
07 FebruaryDescending modulatory pathways
Distribution of EXAM 1 (due start of class, 11 February)
G. Gebhart*
Gebhart (2004) – Descending modulation of pain; Mason (2005) - Ventromedial medulla: Pain modulation and beyond; and (2005) - Deconstructing endogenous pain modulation
11 FebruaryClinical Trails
M. Max*
 
14 FebruaryPain GeneticsM. Max* 
18 FebruaryInjury-induced changes
in afferent signaling
M. Gold*
 
20 FebruaryKen Hargreaves – U. Texas, San Antonio Seminar “A TRP through trigeminal nociceptors”
1105A Scaife Hall
21 FebruaryPre/peri/postoperative pain managementJ. Celly
Anesthesiology
 
25 FebruaryVisceral PainBielefeldt*, Medicine– Gastroenterol. 
28 February
Musculoskeletal painA. Delito
Physical Therapy
 
03 MarchPain - DevelopmentK. Albers*

 

06 MarchSex and Pain
K. Albers* 
10, 13 MarchSpring Break 
17 MarchHIV Pain
R. Arnold, Palliative Care 
19 MarchIrene Tracey – Oxford University  SeminarAllTitle to be announced
20 MarchNeuropathic pain
Distribution of EXAM  2 (due start of class, 24 March)
C. Bernstein
Neurology
 

 

24 MarchInjury-induces changes in
dorsal horn signaling
R. Koerber*

 

27 MarchHeadacheR. Kaniecki,
Director, Headache Center
 
31 March
Psychological aspects of pain assessment and treatmentC. Greco
Psychiatry
 
03 AprilPain and DepressionJ. Karp
Psychiatry
 
07 AprilDorsal column stimulationP. Aguilar
Neurosurgery

 

10 AprilPain Fellows repriseAll
 
14 AprilFellows reprise/Student
Presentations1
All 
16 AprilRobert Gereau –CANCELED SeminarAllAnother speaker Possible
1105A Scaife Hall
17 AprilFellows reprise/Student
Presentations1
All 
21 AprilFinal Exam Week
Fellows reprise/Student
Presentations1
All 

Notes:

* Center for Pain Research faculty

  • Students registered in the course will be asked to select from a list a topic for a ‘term’ paper (10 double spaced pages, not including references, figures or tables).  The paper is Due Monday, 9 April and will constitute about 20% of the course grade.  Students will give an oral presentation (20 min) of the paper/topic at the end of the semester (which will constitute another 20% of the course grade).